Abstract : The monkey pox virus, which causes the viral zoonotic disease, is known as the most significant orthopoxvirus infection following the elimination of smallpox. Monkey pox, a DNA virus belonging to genus Orthopoxvirus, is a zoonotic disease which was first noticed in Congo as a human infection. World Health Organization (WHO) has declared monkey pox as danger to life on June 23, 2022 due to the reporting of successive increase to about 3,000 cases in as much as 50 countries. There is a need to further have in depth understanding of monkey pox and its vaccination.

Keywords :  Monkeypox; orthopoxvirus; viral zoonosis; poxviridae; orthodox virus genus